Protein Phosphatase PP1 Negatively Regulates IRF3 in Response to GCRV Infection in Grass Carp (Ctenopharyngodon idella)
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منابع مشابه
Insights into the Antiviral Immunity against Grass Carp (Ctenopharyngodon idella) Reovirus (GCRV) in Grass Carp
Global fish production from aquaculture has rapidly grown over the past decades, and grass carp shares the largest portion. However, hemorrhagic disease caused by grass carp reovirus (GCRV) results in tremendous loss of grass carp (Ctenopharyngodon idella) industry. During the past years, development of molecular biology and cellular biology technologies has promoted significant advances in the...
متن کاملFunctional Characterizations of RIG-I to GCRV and Viral/Bacterial PAMPs in Grass Carp Ctenopharyngodon idella
BACKGROUND RIG-I (retinoic acid inducible gene-I) is one of the key cytosolic pattern recognition receptors (PRRs) for detecting nucleotide pathogen associated molecular patterns (PAMPs) and mediating the induction of type I interferon and inflammatory cytokines in innate immune response. Though the mechanism is well characterized in mammals, the study of the accurate function of RIG-I in teleo...
متن کاملCase report of chondroma in a grass carp (Ctenopharyngodon idella)
The grass carp (Ctenopharyngodon idella) is a herbivorous, freshwater fish species of the family Cyprinidae, and the only species of the genus Ctenopharyngodon. Neoplasms in fishes are generally less aggressive than neoplasms in mammals and are most commonly discrete, focal and benign neoplasms. A 3-year-old grass carp with a big mass on the vertebrae was referred to the clinic. According to the...
متن کاملGrowth Response of Juvenile Grass Carp (ctenopharyngodon Idella) Fed Isocaloric Diets with Variable Protein Levels
Sixty days feeding experiment was conducted on grass carp fry fed isocaloric diets with variable protein levels in order to evaluate its growth response. Different diet ingredients were analyzed for % age protein, % age fat, % age ash, % fiber, % age moisture contents and energy. Five isoenergetic (17.91 ± 0.02 Kg MJ ) and isolipidic (8.56 ± 0.09 g) diets with varying protein levels PL1 (20%), ...
متن کاملProtective Roles of Grass Carp Ctenopharyngodon idella Mx Isoforms against Grass Carp Reovirus
BACKGROUND Myxovirus resistance (Mx) proteins are crucial effectors of the innate antiviral response against a wide range of viruses, mediated by the type I interferon (IFN-I) signaling pathway. However, the antiviral activity of Mx proteins is diverse and complicated in different species. METHODOLOGY/PRINCIPAL FINDINGS In the current study, two novel Mx genes (CiMx1 and CiMx3) were identifie...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2021
ISSN: 1664-3224
DOI: 10.3389/fimmu.2020.609890